Retatrutide
A triple GIP/GLP-1/glucagon agonist showing >20% weight loss in phase 2, the most powerful incretin in the pipeline.
Verdict, C · Emerging / Mixed
Unprecedented phase-2 weight-loss signal and strong phase-3 enrollment, but no approval, limited independent sourcing, and an expected GLP-1-class safety profile with additional glucagon-axis unknowns. Watch the TRIUMPH readout; buy nothing from the gray market.
Overview
Retatrutide is a triple GIP/GLP-1/glucagon receptor agonist (Eli Lilly) currently in phase-3 TRIUMPH trials with no regulatory approval yet. Phase-2 data demonstrated up to 24% body-weight reduction, the largest in any published incretin trial. Gray-market supply exists but is unverified; the compound is not yet commercially manufactured for consumer use.
PepScore Breakdown, the four axes
Evidence
35% weightHow strong is the published human science?
Sourcing & COA
30% weightOur moatCan a buyer obtain an independently-verified, high-purity version?, our proprietary layer.
Safety & Risk
25% weightWhat is the real-world harm potential?
Practicality
10% weightHow easy is it to actually run a verified version?
Sources & Citations
Every claim cites a primary source. Citations are machine-audited against NCBI, see methodology.
Best-Sourced Vendor
Amino Club
Vendor 83 · AStrong vendor grade (A) and the best verified supply right now for Retatrutide, batch-matched independent COA freshness 90%.
Visit Amino Club ↗Ranked by Source Match = Vendor Grade × batch-COA freshness. Affiliate status is never an input to any grade, and a paying vendor never outranks a non-paying one on a tie.How this works →
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