PepEvolutionLearn Peptides
From beginner to expert, everything you need to understand peptides, protocols, and safe sourcing.
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Peptides 101
New to peptides? Start here. What they are, how they work, and what to know before you begin.
Explore →Research Blog
Evidence-based articles from beginner overviews to clinician-grade regulatory analysis. Cited, no hype.
Explore →Expert Analysis
Curated voices and analysis from researchers, clinicians, and independent specialists in the field.
Explore →Latest Peptide News
FDA Approves Mimrylo (Rusfertide), a First-in-Class Hepcidin Mimetic, for Polycythemia Vera
Aug 28, 2026: FDA approved Mimrylo (rusfertide), the first hepcidin-mimetic drug for adults with polycythemia vera, after VERIFY showed fewer phlebotomies.
FDA Staff Propose Against 503A Listing for BPC-157, TB-500, MOTS-c, KPV, Semax, Epitalon & DSIP
At the July 23-24, 2026 PCAC meeting, FDA staff proposed that all seven peptides under review NOT be added to the 503A Bulks List. Here is what the briefing docs actually say, and what they do not.
The Peptide Industry's Accreditation Illusion: We Checked the Labs Behind Your COAs
Vendors lean on 'ISO 17025' and 'accredited lab' to sell trust. We went to the accreditation registries, A2LA, ANAB, PJLA, IAS, and CMS, and checked. No lab issuing peptide COAs has a publicly verifiable ISO 17025 scope covering peptide purity or identity. Here is the lab-by-lab record, and what actually signals a trustworthy COA.
Recent from the Blog
All articles →Gonadorelin: Native GnRH, Not Kisspeptin and Not a Depot Agonist
Gonadorelin is synthetic native GnRH, a 10-residue hypothalamic peptide. Here is the 1971 sequence, the Belchetz pulse rule, the Hoffman puberty data, and why a catalog vial is not Factrel.
Palopegteriparatide (Yorvipath): The TransCon PTH Prodrug, Not Forteo
Palopegteriparatide is a TransCon prodrug of PTH(1-34), sold as Yorvipath for adult hypoparathyroidism. Here is the PEG-linker chemistry, the PaTHway numbers on the FDA label, and why a catalog teriparatide vial is not that product.
Liraglutide (Saxenda): The Daily GLP-1 That Came Before Wegovy
Liraglutide is Novo Nordisk's once-daily acylated GLP-1 analog. Here is the C16 albumin chemistry, the SCALE obesity data, the LEADER cardiovascular readout, STEP 8 versus weekly semaglutide, and why a catalog vial is not Saxenda.
Ipamorelin vs MK-677: Same Ghrelin Receptor, Not the Same Molecule
MK-677 (ibutamoren) is Merck's oral small-molecule ghrelin mimetic. Ipamorelin is a five-residue peptide. Here is the chemistry, the Nass and Copinschi data, the hip-fracture CHF signal, and why neither is an FDA-approved GH drug.
FOXO4-DRI: The Senolytic Peptide From a 2017 Cell Paper, Not a Longevity Drug
FOXO4-DRI is a D-retro-inverso peptide built to break FOXO4 and p53 binding in senescent cells. Here is the IMR90 biology, the mouse chemotoxicity and kidney data, the 2025 NMR follow-up, and why a catalog vial is not an approved senolytic.
ARA-290 (Cibinetide): The EPO Helix B Peptide That Skips Red Cells
ARA-290 is an 11-amino-acid peptide modeled on erythropoietin helix B. Here is the EPOR and CD131 biology, the 2012 sarcoidosis pilot, the 2017 corneal-nerve phase 2b, and why a catalog vial is not an FDA-approved EPO drug.
Start with the basics
Peptides 101
What peptides are, how they work, and what to know before you start.
Peptide Glossary
Plain-English definitions of 25+ peptides grouped by use, a fast way to get your bearings.
Reconstitution Guide
How to mix peptides, choose syringe type, store vials, and avoid common mistakes.
Dose Calculator
Enter vial size, BAC water, and desired dose, get your exact draw amount.
Dosing guides, what the research shows
Doses used in published studies, reconstitution math, and safety notes, cited, educational, never prescriptive.
BPC-157 Dosage
BPC-157 dosage and reconstitution: doses used in published research, unit math, BAC water examples, half-life and safety notes. Educational only, not medical advice.
Tirzepatide Dosage
Tirzepatide dose titration from the FDA label and SURMOUNT-1 trial, reconstitution math for compounded vials, half-life and safety, cited, not medical advice.
TB-500 Dosage
Doses of TB-500 (thymosin beta-4 fragment) reported in research, weekly loading conventions, reconstitution math and safety notes, cited and educational only.
Semaglutide Dosage
Semaglutide dosage from FDA labels and trials, plus example reconstitution math for research vials. Educational only, not medical advice.
Ipamorelin Dosage
Ipamorelin dosage and reconstitution: research context, unit math, and safety notes. Educational only, not medical advice.
Educational only, not medical advice.This site is for informational purposes only. Nothing here is a prescription, dosing recommendation, or medical guidance. Always consult a licensed healthcare provider.