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AnabolicFully audited

IGF-1 LR3

Long R3 IGF-1

A real anabolic mechanism wrapped in near-zero human safety data and the hardest-to-verify sourcing in the catalog.

Verdict — F · Avoid / High-Risk

A real anabolic mechanism, but near-zero human safety data, a genuine cell-proliferation and hypoglycemia risk, and the hardest-to-verify sourcing in the catalog. Avoid for almost everyone.

Overview

IGF-1 LR3 is a modified insulin-like growth factor with a long half-life and potent anabolic signaling. It also carries a genuine cell-proliferation and hypoglycemia risk, almost no human safety data, and is a fragile protein that labs struggle to verify — making clean sourcing exceptionally difficult.

PepScore Breakdown — the four axes

Evidence

35% weight
21/100

How strong is the published human science?

Human data depth5/40
Regulatory & registry status3/30
Reproducibility & consistency8/20
Mechanism characterized in humans5/10

Sourcing & COA

30% weightOur moat
41/100

Can a buyer obtain an independently-verified, high-purity version? — our proprietary layer.

Independent 3rd-party testing15/35
Verified purity %12/30
COA transparency & batch traceability8/20
Multi-vendor verified availability6/15

Safety & Risk

25% weight
28/100

What is the real-world harm potential?

Documented AEs / toxicity8/40
Contraindication breadth8/25
Regulatory warnings7/20
Therapeutic index / margin5/15

Practicality

10% weight
48/100

How easy is it to actually run a verified version?

Verified-source availability14/35
Cost / value per cycle15/25
Reconstitution & administration12/25
Storage & stability7/15

Sources & Citations

Every claim cites a primary source. Citations are machine-audited against NCBI — see methodology.

Best-Sourced Vendor

Limitless Life Nootropics

Vendor 84 · A

Strong vendor grade (A) and the best verified supply right now for IGF-1 LR3 — batch-matched independent COA freshness 40%.

Visit Limitless Life Nootropics ↗

Ranked by Source Match = Vendor Grade × batch-COA freshness. Affiliate status is never an input to any grade, and a paying vendor never outranks a non-paying one on a tie.How this works →

PepScore31/100 · F
Last gradedJune 28, 2026
Next re-grade triggerA registered human safety trial or a reliable lab verification method would move multiple axes.

Educational only — not medical advice. PepScore is an educational research grade, not a prescription or dosing recommendation. Some vendor links are affiliate links — this never affects grades. Consult a licensed healthcare provider before using any compound.