PepEvolution
HomeRankingsSelank
CognitivePreliminary grade

Selank

A Russian-developed anxiolytic/nootropic peptide with a domestic regulatory record but little Western trial evidence.

Verdict, C · Emerging / Mixed

A reasonably benign anxiolytic peptide with a Russian regulatory track record, but the evidence base barely extends beyond domestic studies and sourcing is unverified. A C, interesting and low-burden for the experienced, not a settled recommendation.

Overview

Selank is a synthetic heptapeptide derived from the immunomodulator tuftsin, developed in Russia as an anxiolytic with reported nootropic and immunotropic effects. It carries a Russian regulatory registration and a small domestic clinical literature suggesting benefit in anxiety, but it has essentially no Western registered-trial evidence and the human data are limited and hard to reproduce internationally. Tolerability appears good in the available studies; sourcing is research-grade and COA verification is the limiting factor.

PepScore Breakdown, the four axes

Evidence

35% weight
49/100

How strong is the published human science?

Human data depth16/40
Regulatory & registry status14/30
Reproducibility & consistency11/20
Mechanism characterized in humans8/10

Sourcing & COA

30% weightOur moat
56/100

Can a buyer obtain an independently-verified, high-purity version?, our proprietary layer.

Independent + portal-verifiable testing20/35
Method transparency (HPLC + MS + endotoxin/sterility, methods stated)14/25
Lot-matched + recent14/25
Independent corroboration8/15

Safety & Risk

25% weight
73/100

What is the real-world harm potential?

Documented AEs / toxicity30/40
Contraindication breadth18/25
Regulatory warnings13/20
Therapeutic index / margin12/15

Practicality

10% weight
66/100

How easy is it to actually run a verified version?

Verified-source availability22/35
Cost / value per cycle17/25
Reconstitution & administration18/25
Storage & stability9/15

Sources & Citations

Every claim cites a primary source. Citations are machine-audited against NCBI, see methodology.

Want a clinical path?

Talk to a licensed provider about Selank and whether it's appropriate for your situation.

Talk to a Provider ↗

Telehealth. Not medical advice, for educational purposes.

PepScore59/100 · C
Last gradedJune 28, 2026
Next re-grade triggerA Western registered trial or a clean multi-vendor COA sweep would lift the grade.

Get the PepEvolution Dispatch

Monthly COA findings, vendor changes, and new grades. Research/educational only, no spam.

Educational only, not medical advice. PepScore is an educational research grade, not a prescription or dosing recommendation. Some vendor links are affiliate links, this never affects grades. Consult a licensed healthcare provider before using any compound.