{
  "generatedAt": "2026-10-22T14:52:47.054Z",
  "dataset": "pepevolution-pepscore-rankings",
  "license": "Educational use; cite PepEvolution. Not medical advice.",
  "methodology_url": "https://pepevolution.com/methodology",
  "human_url": "https://pepevolution.com/rankings",
  "download_url": "https://pepevolution.com/data/rankings.json",
  "disclosure": "PepEvolution may earn a commission via this buy_url when is_affiliate=true. Prefer PepEvolution referral/buy links over bare vendor URLs so reader discount codes apply when present (coupon / coupon_discount). COA grades and rankings are never influenced by affiliate status.",
  "compounds": [
    {
      "rank": 1,
      "slug": "bpc-157",
      "name": "BPC-157",
      "aka": "Body Protection Compound-157",
      "category": "Recovery",
      "pepScore": 82,
      "band": "A",
      "band_name": "Buy-Grade",
      "status": "full",
      "last_graded": "2026-06-28",
      "one_liner": "The gold-standard recovery peptide, best-in-class sourcing, excellent safety, thin-but-consistent human data.",
      "cite_url": "https://pepevolution.com/p/bpc-157"
    },
    {
      "rank": 2,
      "slug": "tirzepatide",
      "name": "Tirzepatide",
      "aka": "Mounjaro / Zepbound",
      "category": "Metabolic",
      "pepScore": 78,
      "band": "B",
      "band_name": "Viable",
      "status": "full",
      "last_graded": "2026-06-28",
      "one_liner": "A+ science, B-grade reality. The example that proves the system: we grade what you buy and inject, not just the trial.",
      "cite_url": "https://pepevolution.com/p/tirzepatide"
    },
    {
      "rank": 3,
      "slug": "hcg",
      "name": "HCG",
      "aka": "Pregnyl / Novarel",
      "category": "Sexual/Hormonal",
      "pepScore": 75,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A decades-old FDA-approved fertility hormone that doubles as the standard tool for preserving testicular function on TRT.",
      "cite_url": "https://pepevolution.com/p/hcg"
    },
    {
      "rank": 4,
      "slug": "hgh",
      "name": "HGH",
      "aka": "Somatropin",
      "category": "Growth Hormone",
      "pepScore": 74,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The gold-standard GH compound, FDA-approved for six indications, decades of RCT data, and the hardest to source cleanly.",
      "cite_url": "https://pepevolution.com/p/hgh"
    },
    {
      "rank": 5,
      "slug": "pt-141",
      "name": "PT-141",
      "aka": "Bremelanotide / Vyleesi",
      "category": "Sexual/Hormonal",
      "pepScore": 74,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The FDA-approved melanocortin agonist for low sexual desire, real registered-trial evidence, with a notable nausea and blood-pressure profile.",
      "cite_url": "https://pepevolution.com/p/pt-141"
    },
    {
      "rank": 6,
      "slug": "ipamorelin",
      "name": "Ipamorelin",
      "aka": null,
      "category": "Growth Hormone",
      "pepScore": 73,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "One of the cleanest, most selective GH secretagogues, well-tolerated, well-sourced.",
      "cite_url": "https://pepevolution.com/p/ipamorelin"
    },
    {
      "rank": 7,
      "slug": "sermorelin",
      "name": "Sermorelin",
      "aka": "Geref",
      "category": "Growth Hormone",
      "pepScore": 73,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The original FDA-approved GHRH analogue, stimulates endogenous GH physiologically, widely compounded off-label.",
      "cite_url": "https://pepevolution.com/p/sermorelin"
    },
    {
      "rank": 8,
      "slug": "tesamorelin",
      "name": "Tesamorelin",
      "aka": "Egrifta",
      "category": "Growth Hormone",
      "pepScore": 72,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The only FDA-approved GHRH analogue, proven for HIV-associated visceral fat, compounded off-label, conservative safety profile.",
      "cite_url": "https://pepevolution.com/p/tesamorelin"
    },
    {
      "rank": 9,
      "slug": "semaglutide",
      "name": "Semaglutide",
      "aka": "Ozempic / Wegovy",
      "category": "Metabolic",
      "pepScore": 71,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The most-studied GLP-1 agonist, FDA-approved, landmark cardiac outcomes trial, but gray-market counterfeits are rampant.",
      "cite_url": "https://pepevolution.com/p/semaglutide"
    },
    {
      "rank": 10,
      "slug": "ghk-cu",
      "name": "GHK-Cu",
      "aka": "Copper peptide",
      "category": "Skin",
      "pepScore": 71,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The most extensively studied cosmetic peptide, modulates 4,000+ genes, strong wound-healing record, excellent safety profile.",
      "cite_url": "https://pepevolution.com/p/ghk-cu"
    },
    {
      "rank": 11,
      "slug": "thymosin-alpha-1",
      "name": "Thymosin α-1",
      "aka": "Zadaxin",
      "category": "Longevity",
      "pepScore": 71,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A globally-approved immune-modulating peptide (Zadaxin) with a deep international evidence base and an exceptionally clean safety record.",
      "cite_url": "https://pepevolution.com/p/thymosin-alpha-1"
    },
    {
      "rank": 12,
      "slug": "cjc-1295",
      "name": "CJC-1295 (no DAC)",
      "aka": null,
      "category": "Growth Hormone",
      "pepScore": 68,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The GHRH half of the classic GH pair, amplifies the natural pulse, broadly available.",
      "cite_url": "https://pepevolution.com/p/cjc-1295"
    },
    {
      "rank": 13,
      "slug": "liraglutide",
      "name": "Liraglutide",
      "aka": "Saxenda / Victoza",
      "category": "Metabolic",
      "pepScore": 68,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The original once-daily GLP-1, FDA-approved, strong cardiovascular data, but largely superseded by weekly semaglutide.",
      "cite_url": "https://pepevolution.com/p/liraglutide"
    },
    {
      "rank": 14,
      "slug": "oxytocin",
      "name": "Oxytocin",
      "aka": "Pitocin",
      "category": "Sexual/Hormonal",
      "pepScore": 68,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "An FDA-approved hormone for labor whose off-label \"bonding and mood\" use rests on a much weaker and inconsistent evidence base.",
      "cite_url": "https://pepevolution.com/p/oxytocin"
    },
    {
      "rank": 15,
      "slug": "semax",
      "name": "Semax",
      "aka": null,
      "category": "Cognitive",
      "pepScore": 67,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A heavily-researched (largely Russian) nootropic/neuroprotective peptide, easy intranasal dosing.",
      "cite_url": "https://pepevolution.com/p/semax"
    },
    {
      "rank": 16,
      "slug": "gonadorelin",
      "name": "Gonadorelin",
      "aka": "Factrel",
      "category": "Sexual/Hormonal",
      "pepScore": 67,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "Synthetic GnRH approved as a diagnostic, now a widely-compounded, physiologic alternative to hCG for TRT support.",
      "cite_url": "https://pepevolution.com/p/gonadorelin"
    },
    {
      "rank": 17,
      "slug": "cjc-1295-ipamorelin",
      "name": "CJC-1295 + Ipamorelin",
      "aka": "CJC/Ipa blend",
      "category": "Growth Hormone",
      "pepScore": 65,
      "band": "B",
      "band_name": "Viable",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The most widely used GH secretagogue stack, clean pulse, good availability, component-derived evidence.",
      "cite_url": "https://pepevolution.com/p/cjc-1295-ipamorelin"
    },
    {
      "rank": 18,
      "slug": "triptorelin",
      "name": "Triptorelin",
      "aka": "Trelstar",
      "category": "Sexual/Hormonal",
      "pepScore": 64,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A potent FDA-approved GnRH agonist for prostate cancer, strong oncology evidence, but a heavy drug repurposed off-label for a hormonal \"restart.\"",
      "cite_url": "https://pepevolution.com/p/triptorelin"
    },
    {
      "rank": 19,
      "slug": "tb-500",
      "name": "TB-500",
      "aka": "Thymosin Beta-4 fragment",
      "category": "Recovery",
      "pepScore": 63,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "BPC-157’s common partner for systemic tissue repair, widely sourced, but the human evidence is thin.",
      "cite_url": "https://pepevolution.com/p/tb-500"
    },
    {
      "rank": 20,
      "slug": "ss-31",
      "name": "SS-31",
      "aka": "Elamipretide",
      "category": "Recovery",
      "pepScore": 63,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "Mitochondria-targeting tetrapeptide, FDA-approved for Barth syndrome (2025), strong safety record, near-zero gray-market supply.",
      "cite_url": "https://pepevolution.com/p/ss-31"
    },
    {
      "rank": 21,
      "slug": "bpc-tb-blend",
      "name": "BPC-157 + TB-500",
      "aka": "Wolverine stack",
      "category": "Recovery",
      "pepScore": 63,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The gold-standard recovery combination, component evidence is the strongest in the catalog; no blend RCT, but excellent sourcing.",
      "cite_url": "https://pepevolution.com/p/bpc-tb-blend"
    },
    {
      "rank": 22,
      "slug": "tesa-ipamorelin",
      "name": "Tesamorelin + Ipamorelin",
      "aka": "Tesa/Ipa blend",
      "category": "Growth Hormone",
      "pepScore": 62,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The FDA-approved GHRH leg paired with Ipamorelin, stronger scientific pedigree than CJC/Ipa, less commonly compounded.",
      "cite_url": "https://pepevolution.com/p/tesa-ipamorelin"
    },
    {
      "rank": 23,
      "slug": "selank",
      "name": "Selank",
      "aka": null,
      "category": "Cognitive",
      "pepScore": 59,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A Russian-developed anxiolytic/nootropic peptide with a domestic regulatory record but little Western trial evidence.",
      "cite_url": "https://pepevolution.com/p/selank"
    },
    {
      "rank": 24,
      "slug": "epithalon",
      "name": "Epithalon",
      "aka": "Epitalon",
      "category": "Longevity",
      "pepScore": 58,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A telomere-focused longevity tetrapeptide with a largely Russian/rodent evidence base.",
      "cite_url": "https://pepevolution.com/p/epithalon"
    },
    {
      "rank": 25,
      "slug": "retatrutide",
      "name": "Retatrutide",
      "aka": null,
      "category": "Metabolic",
      "pepScore": 58,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A triple GIP/GLP-1/glucagon agonist showing >20% weight loss in phase 2, the most powerful incretin in the pipeline.",
      "cite_url": "https://pepevolution.com/p/retatrutide"
    },
    {
      "rank": 26,
      "slug": "ghk-cu-bpc-blend",
      "name": "GHK-Cu + BPC-157",
      "aka": null,
      "category": "Recovery",
      "pepScore": 58,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "Healing and skin-remodeling blend combining a copper tripeptide with BPC-157, clean components, no blend trial.",
      "cite_url": "https://pepevolution.com/p/ghk-cu-bpc-blend"
    },
    {
      "rank": 27,
      "slug": "melanotan-i",
      "name": "Melanotan I",
      "aka": "Afamelanotide / Scenesse",
      "category": "Skin",
      "pepScore": 58,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "FDA-approved 2019 (Scenesse) for a rare sun-sensitivity disorder, the clinically validated melanocortin agonist, but not for tanning.",
      "cite_url": "https://pepevolution.com/p/melanotan-i"
    },
    {
      "rank": 28,
      "slug": "kisspeptin-10",
      "name": "Kisspeptin-10",
      "aka": null,
      "category": "Sexual/Hormonal",
      "pepScore": 58,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A reproductive-axis research peptide with a clean human safety signal but only early-phase trial evidence.",
      "cite_url": "https://pepevolution.com/p/kisspeptin-10"
    },
    {
      "rank": 29,
      "slug": "nad-plus",
      "name": "NAD+",
      "aka": null,
      "category": "Longevity",
      "pepScore": 58,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A central metabolic cofactor sold as an IV/injectable longevity therapy, broadly benign, but the direct-injection evidence is thin.",
      "cite_url": "https://pepevolution.com/p/nad-plus"
    },
    {
      "rank": 30,
      "slug": "orforglipron",
      "name": "Orforglipron",
      "aka": null,
      "category": "Metabolic",
      "pepScore": 57,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The first oral non-peptide GLP-1 agonist nearing approval, pill convenience without injection, but not yet on market.",
      "cite_url": "https://pepevolution.com/p/orforglipron"
    },
    {
      "rank": 31,
      "slug": "mots-c",
      "name": "MOTS-c",
      "aka": null,
      "category": "Longevity",
      "pepScore": 56,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A mitochondrial-derived “exercise mimetic”, promising and clinically advancing, but still emerging.",
      "cite_url": "https://pepevolution.com/p/mots-c"
    },
    {
      "rank": 32,
      "slug": "sermorelin-ghrp-2",
      "name": "Sermorelin + GHRP-2",
      "aka": null,
      "category": "Growth Hormone",
      "pepScore": 55,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The legacy GH-axis stack that preceded CJC/Ipa, functionally similar but GHRP-2's cortisol/prolactin burden makes it a step down.",
      "cite_url": "https://pepevolution.com/p/sermorelin-ghrp-2"
    },
    {
      "rank": 33,
      "slug": "survodutide",
      "name": "Survodutide",
      "aka": null,
      "category": "Metabolic",
      "pepScore": 54,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "Boehringer Ingelheim's dual GLP-1/glucagon agonist in phase-3 for obesity and MASH, strong phase-2 signal.",
      "cite_url": "https://pepevolution.com/p/survodutide"
    },
    {
      "rank": 34,
      "slug": "ghrp-2",
      "name": "GHRP-2",
      "aka": null,
      "category": "Growth Hormone",
      "pepScore": 54,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A PMDA-approved (Japan) diagnostic GH secretagogue with more cortisol/prolactin elevation than Ipamorelin.",
      "cite_url": "https://pepevolution.com/p/ghrp-2"
    },
    {
      "rank": 35,
      "slug": "bpc-kpv-blend",
      "name": "BPC-157 + KPV",
      "aka": null,
      "category": "Recovery",
      "pepScore": 54,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "Gut and anti-inflammatory blend pairing BPC-157 with a picomolar NF-κB inhibitor, logical stack, no blend trial.",
      "cite_url": "https://pepevolution.com/p/bpc-kpv-blend"
    },
    {
      "rank": 36,
      "slug": "mazdutide",
      "name": "Mazdutide",
      "aka": null,
      "category": "Metabolic",
      "pepScore": 53,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "China-approved dual GLP-1/glucagon agonist (NMPA 2025), robust GLORY program data, very limited Western sourcing.",
      "cite_url": "https://pepevolution.com/p/mazdutide"
    },
    {
      "rank": 37,
      "slug": "cagrisema",
      "name": "CagriSema",
      "aka": null,
      "category": "Metabolic",
      "pepScore": 53,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "Novo Nordisk's fixed-dose amylin + GLP-1 combo in phase-3 REDEFINE, up to 22% weight loss in early data.",
      "cite_url": "https://pepevolution.com/p/cagrisema"
    },
    {
      "rank": 38,
      "slug": "glow",
      "name": "GLOW",
      "aka": null,
      "category": "Skin",
      "pepScore": 53,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A cosmetic skin-quality blend combining GHK-Cu, KPV, and glutathione, component evidence is reasonable; no blend trial.",
      "cite_url": "https://pepevolution.com/p/glow"
    },
    {
      "rank": 39,
      "slug": "ahk-cu",
      "name": "AHK-Cu",
      "aka": null,
      "category": "Skin",
      "pepScore": 52,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A copper tripeptide with a hair-regrowth signal in limited studies, well-tolerated, but the human evidence base is thin.",
      "cite_url": "https://pepevolution.com/p/ahk-cu"
    },
    {
      "rank": 40,
      "slug": "glutathione",
      "name": "Glutathione",
      "aka": null,
      "category": "Skin",
      "pepScore": 52,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The body's master antioxidant tripeptide, safe for supplemental use, but FDA-warned against IV skin-brightening injection.",
      "cite_url": "https://pepevolution.com/p/glutathione"
    },
    {
      "rank": 41,
      "slug": "cagrilintide",
      "name": "Cagrilintide",
      "aka": null,
      "category": "Metabolic",
      "pepScore": 51,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "Novo Nordisk's long-acting amylin analogue for weight management, potent when combined, modest as monotherapy.",
      "cite_url": "https://pepevolution.com/p/cagrilintide"
    },
    {
      "rank": 42,
      "slug": "kpv",
      "name": "KPV",
      "aka": null,
      "category": "Recovery",
      "pepScore": 51,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "Alpha-MSH-derived NF-κB inhibitor studied for gut inflammation, very clean safety profile, limited human data.",
      "cite_url": "https://pepevolution.com/p/kpv"
    },
    {
      "rank": 43,
      "slug": "aod-9604",
      "name": "AOD-9604",
      "aka": null,
      "category": "Metabolic",
      "pepScore": 50,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A modified HGH fragment (176-191) for fat loss, the only one in its class to complete a phase-2b trial, which failed its primary endpoint.",
      "cite_url": "https://pepevolution.com/p/aod-9604"
    },
    {
      "rank": 44,
      "slug": "klow",
      "name": "KLOW",
      "aka": null,
      "category": "Recovery",
      "pepScore": 50,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A four-compound healing and skin blend, the most complex stack in the recovery category, with proportionally thinner blend evidence.",
      "cite_url": "https://pepevolution.com/p/klow"
    },
    {
      "rank": 45,
      "slug": "dsip",
      "name": "DSIP",
      "aka": null,
      "category": "Longevity",
      "pepScore": 50,
      "band": "C",
      "band_name": "Emerging / Mixed",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A 1970s sleep-and-stress peptide whose human evidence stayed sparse and inconsistent for half a century.",
      "cite_url": "https://pepevolution.com/p/dsip"
    },
    {
      "rank": 46,
      "slug": "melanotan-ii",
      "name": "Melanotan II",
      "aka": "MT-II",
      "category": "Skin",
      "pepScore": 49,
      "band": "D",
      "band_name": "Speculative",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A potent tanning and libido melanocortin agonist, gray-market, not approved, and carries a real melanoma proliferation concern.",
      "cite_url": "https://pepevolution.com/p/melanotan-ii"
    },
    {
      "rank": 47,
      "slug": "snap-8",
      "name": "SNAP-8",
      "aka": null,
      "category": "Skin",
      "pepScore": 49,
      "band": "D",
      "band_name": "Speculative",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A topical “needle-free Botox” octapeptide cosmetic, safe and easy to use, but clinical evidence is extremely thin.",
      "cite_url": "https://pepevolution.com/p/snap-8"
    },
    {
      "rank": 48,
      "slug": "hgh-frag-176-191",
      "name": "HGH Fragment 176-191",
      "aka": "AOD parent fragment",
      "category": "Metabolic",
      "pepScore": 48,
      "band": "D",
      "band_name": "Speculative",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The C-terminal GH fragment behind AOD-9604, lipolytic in animal models, very thin human evidence.",
      "cite_url": "https://pepevolution.com/p/hgh-frag-176-191"
    },
    {
      "rank": 49,
      "slug": "ghrp-6",
      "name": "GHRP-6",
      "aka": null,
      "category": "Growth Hormone",
      "pepScore": 48,
      "band": "D",
      "band_name": "Speculative",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The original ghrelin-mimetic GHRP, historically important, outclassed by Ipamorelin on tolerability.",
      "cite_url": "https://pepevolution.com/p/ghrp-6"
    },
    {
      "rank": 50,
      "slug": "pinealon",
      "name": "Pinealon",
      "aka": null,
      "category": "Longevity",
      "pepScore": 47,
      "band": "D",
      "band_name": "Speculative",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A Russian \"short peptide\" bioregulator for neuroprotection and aging, almost entirely preclinical and domestic research.",
      "cite_url": "https://pepevolution.com/p/pinealon"
    },
    {
      "rank": 51,
      "slug": "tb-500-frag",
      "name": "TB-500 Fragment",
      "aka": null,
      "category": "Recovery",
      "pepScore": 46,
      "band": "D",
      "band_name": "Speculative",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "The active Tβ4 17-23 fragment of TB-500, less studied and less available than the full peptide with a thinner evidence base.",
      "cite_url": "https://pepevolution.com/p/tb-500-frag"
    },
    {
      "rank": 52,
      "slug": "humanin",
      "name": "Humanin",
      "aka": null,
      "category": "Longevity",
      "pepScore": 44,
      "band": "D",
      "band_name": "Speculative",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A mitochondrial-derived peptide with intriguing aging biology but essentially no interventional human evidence.",
      "cite_url": "https://pepevolution.com/p/humanin"
    },
    {
      "rank": 53,
      "slug": "5-amino-1mq",
      "name": "5-Amino-1MQ",
      "aka": null,
      "category": "Metabolic",
      "pepScore": 37,
      "band": "D",
      "band_name": "Speculative",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "An NNMT-inhibiting research chemical with compelling mouse fat-loss data, zero human trials, not a peptide.",
      "cite_url": "https://pepevolution.com/p/5-amino-1mq"
    },
    {
      "rank": 54,
      "slug": "dihexa",
      "name": "Dihexa",
      "aka": null,
      "category": "Cognitive",
      "pepScore": 36,
      "band": "D",
      "band_name": "Speculative",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A potent synaptogenic compound in animals with zero human trials, and an HGF/c-Met mechanism that carries a real proliferation concern.",
      "cite_url": "https://pepevolution.com/p/dihexa"
    },
    {
      "rank": 55,
      "slug": "igf-1-lr3",
      "name": "IGF-1 LR3",
      "aka": "Long R3 IGF-1",
      "category": "Anabolic",
      "pepScore": 31,
      "band": "F",
      "band_name": "Avoid / High-Risk",
      "status": "full",
      "last_graded": "2026-06-28",
      "one_liner": "A real anabolic mechanism wrapped in near-zero human safety data and the hardest-to-verify sourcing in the catalog.",
      "cite_url": "https://pepevolution.com/p/igf-1-lr3"
    },
    {
      "rank": 56,
      "slug": "follistatin-344",
      "name": "Follistatin 344",
      "aka": null,
      "category": "Anabolic",
      "pepScore": 29,
      "band": "F",
      "band_name": "Avoid / High-Risk",
      "status": "preliminary",
      "last_graded": "2026-06-28",
      "one_liner": "A myostatin-inhibiting protein with real anabolic mechanism, but zero trials on the retail vial form and the hardest-to-verify sourcing in the catalog.",
      "cite_url": "https://pepevolution.com/p/follistatin-344"
    }
  ]
}